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SUMMARY:WW-Colloquium: Dr. Antonia Ressler\, From regeneration to prot
 ection: Biomimetic materials in bone repair\, cancer therapy\, and inf
 ection control
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 000000100000009C388630AD55104BBC5CF79553F48A64
DESCRIPTION:Dr. Antonia Ressler Materials Science and Environmental En
 gineering\, Tampere University of Technology\, Finland From regenerati
 on to protection: Biomimetic materials in bone repair\, cancer therapy
 \, and infection control At least half of population lacks access to e
 ssential health services\, creating an urgent need for innovative and 
 affordable medical solutions. There is pressing need to address major 
 challenges related to the bone diseases. The incidence of bone fractur
 es is increasing globally and bone grafting now stands as the second m
 ost prevalent tissue transplantation. In addition to increased number 
 of bone fractures/defects\, bone cancer is one of the cancers with the
  lowest long-term survival rate. Further\, bacterial resistance is a p
 ersistent global issue driven by the uncontrolled use of antibiotics. 
 It seems that the long feared postantibiotic era is here\, urging new 
 methods to fight infections. Most scaffolds developed for bone regener
 ation lack anticancer and antibacterial functionality\, highlighting t
 he urgent need for multifunctional scaffold designs. The possible solu
 tion is to treat patients with biomimetic scaffolds based on calcium p
 hosphates multi-substituted with different trace elements to obtain a 
 multifunctional scaffold for bone regeneration with antibacterial and 
 anticancer properties. The impact of the selected trace elements\, dif
 ferent scaffold compositions\, and designs was evaluated to gain deep 
 insights into physicochemical properties as well as osteogenic potenti
 al using human stem cells. The effect of trace elements was investigat
 ed\, and selective anticancer properties were determined when selenium
  was used as a substitution element. Furthermore\, the antibacterial e
 ffect against multidrug-resistant bacteria from clinical isolates was 
 investigated for a wide selection of elements\, confirming silver as t
 he gold standard.
DTSTART:20260203T150000Z
DTEND:20260203T170000Z
LOCATION:H14 / Zoom
DTSTAMP:20260622T175655Z
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